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HelpTest Code Troponin T Gen 5 Troponin T Gen 5
Aliases
TnT, Troponin T 5th Generation
Useful For
Troponin is a highly specific marker of myocardial injury. The 5th generation assay has improved sensitivity and a lower limit of detection when compared to previous versions of troponin assays. Elevated levels by the 5th generation assay may be due to acute myocardial infarction or other conditions unrelated to coronary artery disease such as: myocarditis, pulmonary embolism, heart failure, renal failure, sepsis, shock, hypoxia, hypoperfusion, or severe hypertension. Troponin test results (absolute and relative) should be assessed in conjunction with other clinical information.
Patient Preparation
No special patient preparation required
Collection Method
Venous collection
Minimum Volume
- Adults: 0.8ml
- Pediatric: 0.5mL
Container
Lt Green / Plasma Separator / Lithium Heparin
Preferred Specimen
Light Green Top (lithium heparin) plasma
Acceptable Specimens
Plasma:
- Light Geen Top (lithium heparin)
Reference or Target Ranges
| 0 hour result | Interpretation |
|---|---|
| Female ≤14 ng/L Male ≤22 ng/L Unk ≤19 ng/L AND pain onset >2 hours |
Acute myocardial injury less likely, stratify by clinical scenario |
| Other | Indeterminate: 2 hour test recommended |
| >100 ng/L | Acute myocardial injury ruled in |
| 2 hour Delta Value | Interpretation |
| ≤3 ng/L | Myocardial less likely, stratify by clinical scenario |
| 4 – 9 ng/L | Indeterminate: 6 hour test recommended |
| ≥10 ng/L | Changing: Acute myocardial injury ruled in |
| 6 hour Delta Value | Interpretation |
| <12 ng/L | Myocardial injury less likely, stratify by clinical scenario |
| ≥12 ng/L | Changing: Acute Myocardial injury ruled in |
Troponin T Delta value is defined as change from the first reported value of a series of troponin test results during the current admission. Please note that the value resets after intervals of more than 8 hours. ΔTroponin=Troponin (current) – troponin (initial)
Reportable Units
ng/L
Critical Value
Not defined for this assay
Reasons for Rejection
| Hemolysis Threshold | 100 mg/dL |
| Icterus Threshold | 27 mg/dL |
| Lipemia Threshold | 1500 mg/dL |
| Other | QNS, contaminated, improperly Labeled, improper specimen type |
Specimen Stability
| Ambient | 8 hours |
| Refrigerated (4°C to 8°C) | 24 hours |
| Frozen(-40°C to 0°C) | 12 months |
Performance Information
| Days and Time Performed | 24/7 |
| Expected Turn Around Time | Stat: 1 hour Routine: 4 hours |
| Stat Availability | Yes |
| Performing Bench | UH Chemistry, WCH Chemistry |
| Methodology/Method Description | Roche Cobas – Sandwich assay |
Additional Information/Important Notes
For more information and to review the testing flow chart please view the policy in Navex:
Cardiovascular Services – Acute Coronary Syndrome (ACS)Assessment and Triage Low Risk Chest Pain (Walk Ins & Emergency Medical Services (EMS) Transport) – Protocol
Troponin test results (absolute and relative) should be assessed in conjunction with other clinical information such as history, clinical presentation, history, exam, ECG and other cardiac evaluation. Sequential troponin testing may be necessary to document changing concentrations at 2 and 6 hours after initial troponin to evaluate for acute myocardial injury.
CPT Codes
84484