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Test Code CCPLFLREF Cell count, Pleural Fluid Reference Ranges

Refence Ranges

Pleural Fluid
Cutoff Values
Cells Value
White Blood Cells <1000 WBC/uL
Red Blood Cells <100 RB/uL
Notes
  1. Normal differential counts are not well established in the literature. Data published by Noppen, et al, on pleural lavage specimen in normal patients is not symetrically distributed; means and inner quartile ranges are publsihed, but data are likely not sufficient to determine an appropriate cut-off (i.e., the typical 95th percentile). Indeed, Kjeldsberg’s does not include a normal differential cout. However, differential counts may have clinical significance and should be reported.
    Cells Seen in the following conditions:
    Predominance of neutrophils (>50%) Bacterial disease, Pulmonary infarction, Pancreatitis, Early tuberculosis, Subpenic abscess
    Predominance of lymphnocytes (>50%)
    		 Tuberculosis, Viral infection, Malignancy, Chylothorax (a high % of vacuolated macrophages are often seen), Rheumatoid pleuritic, Uremic Effusion
    Eosinophils >10% Infection, Neoplasm, Pulmonary infarction, Connective tissue disorders, Hypersensitivity states, Parasitic infection, Pneumothorax

  2. Transudative effusions may have RBC counts as high as 100,000 RBC/uL; however, Noppen described only few RBC;s in normal pleural fluid (median 46 RBC/uL. Nationally, normal values range from <100 RBC/uL to 100,000 RBC/uL