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Test Code CSP53 TP53 Gene Somatic Mutation Pre-Analysis Cell Sorting, Varies


Specimen Required


Only orderable as a reflex. For more information see P53CA / Hematologic Neoplasms, TP53 Somatic Mutation, DNA Sequencing Exons 4-9, Varies.

 

Specimen Type: Blood

Container/Tube: Lavender top (EDTA) or yellow top (ACD solution B)

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send whole blood specimen in original tube. Do not aliquot.

3. Label specimen as blood.

Specimen Stability Information: Ambient/Refrigerate <10 days


Secondary ID

607599

Useful For

Determination of B-cell content and confirmation the presence of a clonal B-cell population evaluating chronic lymphocytic leukemia patients prior to TP53 variant analysis

Method Name

Only orderable as a reflex. For more information see P53CA / Hematologic Neoplasms, TP53 Somatic Mutation, DNA Sequencing Exons 4-9, Varies.

 

Flow Cytometric Cell Selection

Reporting Name

TP53 Pre-Analysis Cell Sorting, V

Specimen Type

Varies

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred) 10 days
  Refrigerated  10 days

Reject Due To

Gross hemolysis Reject
Fully clotted Reject

Reference Values

Only orderable as a reflex. For more information see P53CA / Hematologic Neoplasms, TP53 Somatic Mutation, DNA Sequencing Exons 4-9, Varies.

Method Description

Peripheral blood specimens from chronic lymphocytic leukemia patients are analyzed by fluorescent activated cell sorting and enrichment to determine B-cell content and confirm the presence of a clonal B-cell population.(Instruction manual: BD FACSMelody Cell Sorter User's Guide. Revision 3. BD Biosciences; 03/2020)

Day(s) Performed

Specimens processed: Monday through Sunday

Results reported: Monday through Friday

Report Available

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88184-Flow cytometry, first cell surface, cytoplasmic or nuclear marker

88185 x 4-Each additional marker

LOINC Code Information

Result ID Test Result Name Result LOINC Value
607678 TP53 Pre-Analysis Cell Sort No LOINC Needed
607687 Final Diagnosis 22637-3