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Test Code Histone Ab Histone Antibody

Useful For

Antibody to Histone is associated with drug-induced Systemic Lupus Erythematosus (SLE)

Patient Preparation

No special patient preparation required

Collection Method

Venous collection

Minimum Volume

2 mL

Container

Gold Top Serum Separator

Preferred Specimen

Serum

Acceptable Specimens

Serum:

  • Gold Top SST

  • Red Top

Plasma:
  • Light Geen Top (lithium heparin)

Reference or Target Ranges

Negative

Reportable Units

Positive/Negative

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold
 N/A
Icterus Threshold
 N/A
Lipemia Threshold
 N/A
Other
 QNS, contaminated, improperly labeled, improper specimen type

Specimen Stability

Ambient
 48 Hours
Refrigerated (4°C to 8°C)
 14 Days
Frozen(-70°C to 0°C)
 Indefinitely

Performance Information

Days and Time Performed
 Every 2 Weeks
Expected Turn Around Time
 2 Weeks
Stat Availability
 No
Performing Bench
 ANA
Methodology/Method Description
 Manual – Indirect Immunofluorescence (mouse/rat kidney substrate)

Additional Information/Important Notes

Positivity for Histone requires a high titer positive homogeneous FANA

CPT Codes

86255