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Test Code MYGLU Myoglobin, Random, Urine

Reporting Name

Myoglobin, Random, U

Useful For

Confirming the presence of a myopathy

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Supplies: Urine Myoglobin Transport Tube (T691)

Container/Tube: Plastic, 5-mL urine myoglobin transport tube

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a preservative-free, random urine specimen.

2. If specimen is at ambient temperature, aliquot the urine to a urine myoglobin transport tube within 1 hour of collection. Refrigerate specimen.

3. If specimen is at refrigerate temperature, aliquot the urine to a urine myoglobin transport tube within 2 hours of collection.

Additional Information: Urinary myoglobin is highly unstable unless alkalinized with sodium carbonate preservative.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated 7 days MYOGLOBIN TRANSPORT TUBE

Reference Values

0-24 mcg/L

Reference values have not been established for patients younger than 18 years; however myoglobin is not expected to be detectable in urine.

Day(s) Performed

Monday through Sunday

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83874

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MYGLU Myoglobin, Random, U 2641-9

 

Result ID Test Result Name Result LOINC Value
MYGLU Myoglobin, Random, U 2641-9

Method Description

This myoglobin test is a sandwich-principal assay. The first incubation is 9 mcL of sample, a biotinylated monoclonal myoglobin-specific antibody, and a monoclonal myoglobin-specific antibody labeled with a ruthenium complex, which react to form a sandwich complex. In the second incubation, the complex becomes bound to the solid phase via interaction of biotin and streptavidin after addition of streptavidin-coated microparticles. The reaction mixture is aspirated into the measuring cell where the microparticles are magnetically captured onto the surface of the electrode. Results are determined via a calibration curve, which is instrument specifically generated by 2-point calibration, and a master curve provided via the cobas link.(Package insert: Elecsys Myoglobin. Roche Diagnostics; 10/2022)

Report Available

1 to 2 days

Reject Due To

Use of any transport tube other than urine myoglobin transport tube Reject

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Secondary ID

621087