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Test Code VZV IgG Varicella Zoster Antibody


Varicella Ab

Useful For

Intended for the qualitative detection of specific IgG antibodies to Varicella Zoster Virus in human serum as an aid to determine previous infection of VZV

Patient Preparation

No special patient preparation required

Collection Method

Venous collection

Minimum Volume

1 mL


Gold Top Serum Separator

Preferred Specimen


Acceptable Specimens


  • Gold Top SST

  • Red Top

Reference or Target Ranges

  • <135 – Negative – Absence of detectable VZV IgG antibodies. Does not rule out acute infection during incubation and early stages.
  • >165 – Positive – Presence of detectable VZV IgG antibodies. Does not indicate active infection or stage of disease.
  • 135 – 165 Equivocal – Repeat the test. If repeated result is equivocal, a second collection should be tested.

Reportable Units

Index value and interpretation

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold
Icterus Threshold
Lipemia Threshold
QNS, contaminated, improperly labled, improper specimen type.

Specimen Stability

Refrigerated (2°C to 8°C)
7 Days
Frozen(<-20°C to 0°C)

Performance Information

Days and Time Performed
Monday – Friday 8 AM – 4:30 PM
Expected Turn Around Time
Within 3 days of arrival in lab
Stat Availabilty
Performing Bench
Special Chemistry
Methodology/Method Description
DiaSorin Liasion XL – Chemiluminescence immunoassay (CLIA)

Special Handling

Centrifuge specimen as early as possible after clotting; transfer serum to a plain polypropylene tube and refrigerate.

Additional Information/Important Notes

The result alone is not diagnostic and should be considered with other clinical data and patient symptoms. Results from immunosuppressed patient should be interpreted with caution. Performance characteristics with individuals vaccinated with VZV (ROD strain) have not been established.

CPT Codes