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Test Code AMH1 Antimullerian Hormone, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Secondary ID

608824

Useful For

Assessing ovarian status, including ovarian reserve and responsiveness, as part of an evaluation for infertility and assisted reproduction protocols

 

Assessment of menopausal status, including premature ovarian failure

 

Evaluation of infants with ambiguous genitalia and other intersex conditions

 

Evaluating testicular function in infants and children

 

Monitoring individuals with antimullerian hormone-secreting ovarian granulosa cell tumors

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Reporting Name

Antimullerian Hormone, S

Specimen Type

Serum

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  180 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject-acceptable to 1000 mg/dL
Gross lipemia OK
Gross icterus Reject-acceptable to 66 mg/dL

Reference Values

Males

<2 years: 18-283 ng/mL

2-12 years: 8.9-109 ng/mL

>12 years: <13 ng/mL

 

Females

<3 years: 0.11-4.2 ng/mL

3-6 years: 0.21-4.9 ng/mL

7-11 years: 0.36-5.9 ng/mL

12-14 years: 0.49-6.9 ng/mL

15-19 years: 0.62-7.8 ng/mL

20-24 years: 1.2-12 ng/mL

25-29 years: 0.89-9.9 ng/mL

30-34 years: 0.58-8.1 ng/mL

35-39 years: 0.15-7.5 ng/mL

40-44 years: 0.03-5.5 ng/mL

45-50 years: <2.6 ng/mL

51-55 years: <0.88 ng/mL

>55 years: <0.03 ng/mL

Method Description

The Roche Elecsys AMH (anti-Mullerian hormone) assay is a 2-site immunometric sandwich assay using electrochemiluminescence detection. Patient specimen, biotinylated monoclonal AMH-specific antibody, and monoclonal AMH-specific antibody labeled with a ruthenium react to form a complex. Streptavidin-coated microparticles act as the solid phase to which the complex becomes bound. Voltage is applied to the electrode inducing a chemiluminescent emission from the ruthenium, which is then measured against a calibration curve to determine the amount of AMH in the patient specimen.(Package insert: Elecsys AMH, Roche Diagnostics; 2.0 English, 10/2022)

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82166

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMH1 Antimullerian Hormone, S 83104-0

 

Result ID Test Result Name Result LOINC Value
AMH1 Antimullerian Hormone, S 83104-0

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.