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Test Code B2 Panel Anti-Beta 2 Glycoprotein-I Panel (IgG, IgA, IgM)

Useful For

To aid in the diagnosis of thrombotic disorders related to primary & secondary anti-phospholipid syndrome (APS)

Patient Preparation

No special patient preparation required

Collection Method

Venous collection

Minimum Volume

2 mL

Container

Gold Top Serum Separator

Preferred Specimen

Serum

Acceptable Specimens

Serum:

  • Gold Top SST

  • Red Top

Plasma:
  • Light Geen Top (lithium heparin)

Reference or Target Ranges

B2 IgA:
 <20
B2 IgG:
 <20
B2 IgM:
 <20

Reportable Units

RLU

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold
 N/A
Icterus Threshold
 N/A
Lipemia Threshold
 N/A
Other
 QNS, contaminated, improperly labeled, improper specimen type

Specimen Stability

Ambient
 N/A
Refrigerated (4°C to 8°C)
 48 Hours
Frozen(-70°C to 0°C)
 Indefinitely

Performance Information

Days and Time Performed
 Tuesday, Thursday, and Friday 7 AM – 4 PM
Expected Turn Around Time
 Within 7 days of arrival in lab
Stat Availability
 No
Performing Bench
 ANA
Methodology/Method Description
 Bioflash – Chemilluminescence

Additional Information/Important Notes

Strongly positive results for B2GP1 IgG and IgM antibodies are diagnostic criterion for antiphospholipid syndrome (APS). Lesser levels of B2GP1 antibodies and antibodies of IgA isotype may occur in patients with clinical signs of APS, but the results are not considered diagnostic. B2GP1 antibodies must be detected on 2 or more occasions at least 12 weeks apart to fulfill the laboratory diagnostic criteria for APS.

CPT Codes

86146 x3

Panel Components

  • B2 IgA
  • B2 IgG
  • B2 IgM