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HelpTest Code CATN Calcitonin, Serum
Reporting Name
Calcitonin, SUseful For
Aids in the diagnosis and follow-up of medullary thyroid carcinoma
Aids in the evaluation of multiple endocrine neoplasia type II and familial medullary thyroid carcinoma
This test is not useful for evaluating calcium metabolic diseases.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. After collection, immediately place specimen on ice.
2. Refrigerate specimen during centrifugation and immediately transfer serum to a plastic vial.
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 90 days | |
| Refrigerated | 24 hours | ||
| Ambient | 8 hours |
Reference Values
Pediatric
1 month: ≤34 pg/mL
2 months: ≤31 pg/mL
3 months: ≤28 pg/mL
4 months: ≤26 pg/mL
5 months: ≤24 pg/mL
6 months: ≤22 pg/mL
7 months: ≤20 pg/mL
8 months: ≤19.0 pg/mL
9 months: ≤17.0 pg/mL
10 months: ≤16.0 pg/mL
11 months: ≤15.0 pg/mL
12-14 months: ≤14.0 pg/mL
15-17 months: ≤12.0 pg/mL
18-20 months: ≤10.0 pg/mL
21-23 months: ≤9.0 pg/mL
2 years: ≤8.0 pg/mL
3-9 years: ≤7.0 pg/mL
10-15 years: ≤6.0 pg/mL
16 years: ≤5.0 pg/mL
Adults
17 years and older:
Males: ≤14.3 pg/mL
Females: ≤7.6 pg/mL
For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.
Day(s) Performed
Monday through Saturday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82308
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CATN | Calcitonin, S | 1992-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CATN | Calcitonin, S | 1992-7 |
Method Description
Testing is performed on the Roche Cobas. The Roche human calcitonin (hCT) assay is a sandwich electrochemiluminescence immunoassay that employs a biotinylated monoclonal hCT-specific antibody and a monoclonal hCT-specific antibody. Calcitonin in the specimen reacts with both the biotinylated monoclonal hCT-specific antibody and the monoclonal hCT-specific antibody labeled with a ruthenium complex, forming a sandwich complex. Streptavidin-coated microparticles are added and the mixture is aspirated into the measuring cell where the microparticles are magnetically captured onto the surface of the electrode. Unbound substances are then removed with ProCell. Application of voltage to the electrode induces the chemiluminescent emission, which is then measured.(Package insert: Elecsys Calcitonin. Roche Diagnostics; V 2.0, 12/2021)
Report Available
1 to 3 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Method Name
Electrochemiluminescence Immunoassay
Secondary ID
9160Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.