Sign in →

Test Code DCORT 11-Deoxycortisol, Serum

Secondary ID

46920

Useful For

Diagnostic workup of patients with congenital adrenal hyperplasia

 

Part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency

 

Part of metyrapone testing in the differential diagnostic workup of Cushing syndrome

Testing Algorithm

For more information see Steroid Pathways.

Special Instructions

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

11-Deoxycortisol, S

Specimen Type

Serum


Necessary Information


Indicate if specimen was collection before or after metyrapone administration.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Morning (8 a.m.) specimen is preferred.

2. Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

≤18 years: <344 ng/dL

>18 years: 10-79 ng/dL

 

For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.

Method Description

The specimen and an internal standard are assayed by liquid chromatography tandem mass spectrometry. The analyte is detected by multiple-reaction monitoring.(Unpublished Mayo method)

Day(s) Performed

Tuesday

Report Available

3 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82634

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DCORT 11-Deoxycortisol, S 1657-6

 

Result ID Test Result Name Result LOINC Value
46923 11-Deoxycortisol, S 1657-6