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HelpTest Code HIT-Ab HIT Antibody with Reflex to Serotonin Release Assay (SRAU)
Useful For
Heparin-induced thrombocytopenia (HIT) is an immune complex mediated disorder that can cause morbidity and mortality in patients receiving heparin therapy. Anticoagulant is administered to prevent thrombosis; however, the major clinical event in HIT is an increased risk for venous and/or arterial thrombosis.
Patient Preparation
No special patient preparation required
Collection Method
Venous Draw
Container
Light Blue Sodium Citrate and Red Top, Serum
Preferred Specimen
2.7mL Lt. Blue (3.2% NaCitrate) and Red Top
Acceptable Specimens
1.8 mL Lt. Blue (3.2% NaCitrate) and Red Top
Reference or Target Ranges
Negative <1.00 , Positive ≥1.00
Lower Limit of Detection: 0.6 U/mL
Upper Limit of Detection: 16 U/mL
Reportable Units
U/mL
Reasons for Rejection
| Hemolysis Threshold | N/A |
| Icterus Threshold | N/A |
| Lipemia Threshold | N/A |
| Interfering Subtances/Other |
Specimen Stability
| Ambient | 4 hours |
| Refrigerated (4°C to 8°C) | N/A |
| Frozen(-70°C to -20°C) | 4 weeks @ -20oC, 1 year @-80oC: Must be double spun and frozen within 4 hours of draw |
Performance Information
| Days and Time Performed | Batched 24 Hours |
| Expected Turn Around Time | Batched 24 Hours |
| Stat Availability | No |
| Performing Bench | Coagulation |
| Methodology/Method Description | Werfen ACL TOPS - Latex Immunoturbidimetric Assay |
Reflex Testing
First Positive Result, Mayo send out Serotonin Release Assay
CPT Codes
86022
82542 (if necessary) SRAU - Mayo