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HelpTest Code IGGS4 IgG4, Immunoglobulin Subclasses, Serum
Reporting Name
IgG4, Ig SubclassesUseful For
Supporting the diagnosis of IgG4-related disease
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
This test only quantitates the IgG4 protein. If quantitation of all IgG subclass types is desired, order IGGS / IgG Subclasses, Serum.
Specimen Required
Patient Preparation: Fasting preferred but not required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Ambient | 14 days | ||
| Frozen | 14 days |
Reference Values
0-<5 months: ≤19.8 mg/dL
5-<9 months: ≤20.8 mg/dL
9-<15 months: ≤22.0 mg/dL
15-<24 months: ≤23.0 mg/dL
2-<4 years: ≤49.1 mg/dL
4-<7 years: ≤81.9 mg/dL
7-<10 years: 1.0-108.7 mg/dL
10-<13 years: 1.0-121.9 mg/dL
13-<16 years: ≤121.7 mg/dL
16-<18 years: ≤111.0 mg/dL
≥18 years: 2.4-121.0 mg/dL
Day(s) Performed
Monday through Friday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82787
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| IGGS4 | IgG4, Ig Subclasses | 2469-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| IGGS4 | IgG4, Ig Subclasses | 2469-5 |
Method Description
The determination of the soluble antigen concentration by turbidimetric methods involves the reaction with specific antiserum to form insoluble complexes. When light is passed through the suspension formed a portion of the light is transmitted and focused onto a photodiode by an optical lens system. The amount of transmitted light is indirectly proportional to the specific protein concentration in the test sample.
Concentrations are automatically calculated by reference to a calibrations curve stored within the instrument.(Package inserts: Optilite IgG4. The Binding Site Group, Ltd: ver.23, 07/2019)
Report Available
1 to 2 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Method Name
Turbidimetry