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Test Code LMW Hep Low Molecular Weight Heparin Assay

Aliases

Anti-Xa

Useful For

Low molecular weight heparins (LMWH) are used for the prevention and treatment of thromboembolic diseases. The quantitative determination of LMWH are useful for monitoring treatment efficacy.

Patient Preparation

No special patient preparation required

Special Collection Instructions

Properly filled 9:1 ratio (blood to anticoagulant); 3.2% NaCitrate tube

Collection Method

Venous Draw; properly filled 9:1 ratio (blood to anticoagulant)

Minimum Volume

0.5 ml of plasma from a properly filled 1.8 mL or 2.7 mL NaCitrate (light blue) tube

Container

Light Blue Sodium Citrate
 

Preferred Specimen

2.7mL Lt. Blue (3.2% NaCitrate)

Acceptable Specimens

1.8 mL Lt. Blue (3.2% NaCitrate) tube

Reference or Target Ranges

Low Dose: 0.2 – 0.4 Anti-Xa units/mL
High Dose: 0.6 – 1.1 Anti-Xa units/mL

Reportable Units

IU/mL

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold If visible – reject
Icterus Threshold If visible – reject
Lipemia Threshold If visible – reject
Interfering Subtances/Other Short draws, over draws, clotted, improperly labeled, hemolyzed, lipemic or icteric samples, samples > 4 hours from collection

Specimen Stability

Ambient 4 hrs; Must be spun within 1 hour of collection
Refrigerated (4°C to 8°C) N/A
Frozen(-700°C to 00°C) 15 Days@ -20°C; 1 year @ -70°C

Performance Information

Days and Time Performed 24/7
Expected Turn Around Time Stat:1 hour on arrival to lab
Routine:4 hours on arrival to lab
Stat Availability Yes
Performing Bench Coagulation
Methodology/Method Description UH: Werfen ACL TOPS

Special Handling

Once sample is received in Lab- testing must be performed on Platelet Poor Plasma

Additional Information/Important Notes

Specimen will be rejected if received in laboratory > 1 hour after collection.

CPT Codes

85520