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Test Code Tryptase Tryptase 

Important Note

Sample collection should not occur earlier than 15m from onset and up to 3 hrs after the suspected incident. The time between reaction and sample should be noted. 

To confirm the return to baseline levels an additional sample should be collected 24-48hrs after. 

Useful For

In vitro quantitative measurement of tryptase in human serum or plasma brought on by mast cell activation syndrom or anaphylaxis.

Patient Preparation

No special preparation required. 

Collection Method

Venous collection

Minimum Volume

1 mL 

Container

Gold Top Serum Separator

Preferred Specimen

Serum

Acceptable Specimens

Serum:

  • Gold Top SST
  • Red Top

Plasma: 

  • EDTA 

Reference or Target Ranges

Normal: ≤ 11μg/l 

 

Note: In patients with systemic mastocytosis levels of tryptase are, in general, persistently elevated above 20 μg/l.

Additionally, Baseline tryptase levels in the range of approximately 10-20 μg/l reflect an increased mast cell burden indicating an increased risk in patients with history of severe anaphylactic reaction

Reportable Units

μg/l

Critical Value

None defined for this assay.

Reasons for Rejection

Hemolysis Threshold N/A
Icterus Threshold N/A
Lipemia Threshold N/A
Other QNS, contaminated, improperly labled, improper specimen type. Other reasons deemed appropriate by qualified laboratorians. 

Specimen Stability

Ambient N/A
Refrigerated (2°C to 8°C) 7 Days
Frozen(<-20°C to 0°C) 1 year

Performance Information

Days and Time Performed Batched Monday – Friday 8 AM – 4:30 PM
Expected Turn Around Time Within 3 days of arrival in lab
Stat Availabilty No
Performing Bench Special Chemistry
Methodology/Method Description ImmunoCap 250 

CPT Code

83520