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Test Code U Myo Urine, Myoglobin

Important Note

Only orderable if CK (Creatine Kinase) has been done in last 24 hours and has a result of >5,000.

Useful For

Myoglobin facilitates the transfer or transport of oxygen from the extacellular fluid into the muscle cells. Whenever there is severe injury to striated muscle tissue, considerable quantities of myoglobin are released into the extracellular fluid, eventually enter the blood, and are then excreted by the kidneys. Myoglobinuria may occur following crush injuries to the extremities, after high voltage electric shock and occasionally after severe muscular exertion.

Patient Preparation

No special patient preparation required

Collection Method

Clean catch urine

Minimum Volume

5 mL

Container

Sterile Cup

Preferred Specimen

Urine in Sterile container

Acceptable Specimens

Urine in Sterile container

Reference or Target Ranges

Negative

Reportable Units

Positive/Negative

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold N/A
Icterus Threshold N/A
Lipemia Threshold N/A
Other QNS, improperly labeled, improper container, specimen > 2 hours old

Specimen Stability

Ambient 2 hours
Refrigerated (2°C to 8°C) N/A
Frozen(-70°C to 0°C) N/A

Performance Information

Days and Time Performed 24/7
Expected Turn Around Time STAT: Within 1 hour of arrival in lab
Routine: Within 4 hours of arrival in lab
Stat Availabilty Yes
Performing Bench UH UA
Methodology/Method Description Amicon Ultra – 15 Centrifugal Filters Ultracel – 30K

Additional Information/Important Notes

Limitations of Procedure

  • Low sample recovery in the concentrate can be due to absorptive losses, over-concentration, or passage of sample through the membrane.
  • The Amicon Filter Unites combined with the Siemens Multistix 10 SGs has a sensitivity of 150-620 mcg/L in the detection of myoglobin.

CPT Codes

81005